In this brief commentary, we share our experience of obtaining informed consent from older persons living in the community, dependent on their sons, daughters or in-laws. We present a scenario in which for our community-based cluster randomised controlled trial on ...

Indira Chakravarthi’s critique relates to our paper published in the British Medical Journal in 2021 titled “Effect of screening by clinical breast examination on breast cancer incidence and mortality after 20 years: prospective, cluster randomised controlled trial...

This article discusses issues of ethical concern in the conduct of a prospective, cluster randomised controlled trial for evaluating effectiveness of screening by clinical breast examination for downstaging of breast cancer, and in reducing mortality from the disea...

Background: Global healthcare research suffers from inequalities, favouring high-income countries, which hampers fair healthcare access. Low and lower-middle-income nations face limited participation and editorial bias, posing concerns for research integrity. Poten...

Off-label use of drugs, when not supported by sound scientific evidence, hinders the development of evidence-based medicine and therapeutic innovation, is costly to the healthcare system, and exposes patients to unnecessary risks, including mortality, for an uncert...