Dublin Core | PKP Metadata Items | Metadata for this Document | |
1. | Title | Title of document | Testing a low-cost approach to giving eRIG for rabies PEP: Ethical issues |
2. | Creator | Author's name, affiliation, country | Richard A Cash; Department of Global Health and Population, Harvard TH Chan School of Public Health, Boston, Massachusetts, USA |
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4. | Description | Abstract | Ethical concerns in using a lower dose of equine rabies immune globulin (eRIG) to irrigate wounds from dog bites to prevent rabies are discussed. A lower dose of eRIG was used because of a general shortage of eRIG and the high market cost in the Himachal Pradesh state of India. The cost and availability of drugs in low- and middle-income countries (LMIC) often necessitates testing a lower dose of a vaccine or treatment than that recommended by international organizations (eg WHO). It raises the issue that recommendations may be designed for higher income countries without taking into consideration issues of supply and cost. Secondly a case-control design to compare dosages or delivery systems is usually not an option so investigators must often use historical data for comparison or other study designs. The ethical issues in the testing of drugs and vaccines in LMIC must be continuously reviewed by the international community |
5. | Publisher | Organizing agency, location | Forum for Medical Ethics Society |
6. | Contributor | Sponsor(s) | |
7. | Date | (YYYY-MM-DD) | 2019-05-06 |
8. | Type | Status & genre | |
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9. | Format | File format | HTML , PDF |
10. | Identifier | Uniform Resource Identifier | https://ijme.in/articles/testing-a-low-cost-approach-to-giving-erig-for-rabies-pep-ethical-issues/ |
11. | Source | Title; vol., no. (year) | Indian Journal of Medical Ethics;: Hope lies in informed struggle |
12. | Language | English=en | en |
13. | Relation | Supp. Files | |
14. | Coverage | Geo-spatial location, chronological period, research sample (gender, age, etc.) | |
15. | Rights | Copyright and permissions | All articles published in IJME are available on its website free of charge. The copyright for published material belongs to IJME/FMES. IJME freely permits the reprint (or reproduction on a website) of articles from the journal, as long as this is for non-commercial use and appropriate credit is given to the author and the journal and publication details are mentioned. The commercial use of our content can be made only after obtaining permission from and on payment to IJME. This is intended to support production of the journal. |